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Endometrial dating based on histomorphology

As such, the material is presented in a less traditional fashion.

Conventional histopathologic classifications remain an integral part of the text, but the various chapters focus on a clinically oriented approach to the microscopic diagnosis of common problems.

Gesta-tional trophoblastic disease is rare in routine practice.

Furthermore, tro-phoblast of abortion specimens, including the trophoblast of the implantation site, usually receives little scrutiny.

Accordingly, in this edition the problems, pitfalls, and utility of this valuable diagnostic adjunct have received greater attention.

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Metaplasia and other benign changes can mimic hyperplasia and carcinoma, so the text focuses on these lesions in detail. The chapter on polyps was revised to further clarify the terminology of these common lesions, as they demonstrate a wide spectrum of morphologic features. Because hydatidiform mole is now commonly recognized at an earlier stage of gestation, the features of these “early moles” are dis-cussed in greater detail. Diagnosis of Endometrial Biopsies and Curettings Second Edition Michael T. (1994), describe the morphologic features and classification of benign and malignant endometrial lesions, but little attention is given to the subtle differences between physiologic changes and pathologic conditions and the artifacts of biopsy and processing. Mazur, MD Clinical Professor of Pathology, State University of New York, Upstate Medical University, Syracuse, New York, and Clear Path Diagnostics, Syracuse, New York Robert J. Te Linde Distinguished Professor, Departments of Gynecology, Obstetrics and Pathology, The Johns Hopkins Hospital, and The Johns Hopkins University School of Medicine, Baltimore, Maryland Diagnosis of Endometrial Biopsies and Curettings A Practical Approach Second Edition With 230 Illustrations, 77 in Full Color Michael T. In addition, micro-scopic findings that can be safely ignored because they have no clinical bearing are generally not discussed in standard texts. Most importantly, however, the text continues its focus on those aspects of endometrial biopsy interpretation that can be especially vexing, such as the diagnosis of atypical hyperplasia, grading of endome-trial carcinoma, and the myriad of benign changes and artifacts that can be confusing to the pathologist. Information about the distinc-tion of endometrial carcinoma from endocervical adenocarcinoma also was significantly revised. Although the entire book has been revised, several areas received par-ticular attention. In addition, a large number of color illustrations have been added to help the reader understand the morphologic changes described in the text. For example, the individual chapters address the clinical ques-tions and specifics of reporting the findings, aspects that vary according to the patient’s age and the clinical circumstances. One important subject is that of changes in the endometrium induced by breakdown and bleeding, independently of the underlying pathology.


  1. May 18, 2017. There are several histologic types of endometrial carcinoma EC. Endometrioid histology is the most common, and this typically presents at an early stage with abnormal uterine bleeding, and is most common in postmenopausal women. Other histologic types may have more aggressive clinical behavior.

  2. Review on micronized progesterone for endometrial protection, an international expert panel's recom- mendations. oral. MP. 200 mg/day days. 1–1. 2. Oral. CEE. 0.625 mg/day. No. Yes baselin e and annually without regard to woman's menstrual cycle. Histology in placebo gro up. n. =. Thus, the largest study to date.

  3. Mar 30, 2012. Histomorphological changes of the endometrium throughout the menstrual cycle have been described over half a century ago by Noyes Noyes et al. 1950 where particular features of the endometrial histology were correlated to specific days of the menstrual cycle allowing the dating of endometrial.

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